Introduction to Intravaginal ring (IVR) and its application in various drug delivery system

Introduction to Intravaginal ring (IVR) and its application in various drug delivery system

A composite vaginal ring containing a safe and effective amount pharmaceutically active medicament and physiological acceptable synthetic resin using selective mold. The active medicament dissolved or uniformly suspended in an elastomeric, cross – linked dimethyl polysiloxane resin. The intravaginal ring (IVR) has a cross-sectional diameter in a range of about 2.5 to 15 mm and outer diameter in a range of about 40 to 65 mm. Polydimethylsiloxane having vinyl groups on both ends. The resultant compositions are characterized by good physical properties and a constant rate of drug release in the body over long periods of time. Organopolysiloxane in which drug is encapsulated having a regular, uniform and prolonged drug dispensation rate, hence to such carriers are used for the production of medicinal agents. Organopolysiloxane elastomers are also known to be suitable carrier materials for depot drug preparations. Providing long-term treatment in a living organism, since they are neither degraded nor resorbed by the organism and show a good tissue compatibility as compared to other synthetic polymers. Read More about Advantages of Intra-vaginal route of drug administration.